KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS
All Species:
28.18
Human Site:
T589
Identified Species:
51.67
UniProt:
O95271
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95271
NP_003738.2
1327
142039
T589
A
K
M
N
A
L
D
T
L
G
Q
T
A
L
H
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
T589
A
K
M
N
A
L
D
T
L
G
Q
T
A
L
H
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
T589
A
K
M
N
A
L
D
T
L
G
Q
T
A
L
H
Dog
Lupus familis
XP_849388
1327
142003
T589
A
K
M
N
A
L
D
T
L
G
Q
T
A
L
H
Cat
Felis silvestris
Mouse
Mus musculus
NP_780300
1320
140926
S582
A
K
M
N
A
L
D
S
L
G
Q
T
A
L
H
Rat
Rattus norvegicus
NP_001101077
1166
126761
S490
E
G
V
S
L
G
H
S
E
A
D
R
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
T582
A
K
M
N
A
L
D
T
L
G
Q
T
A
L
H
Chicken
Gallus gallus
Q5F478
990
107379
A314
K
S
P
L
H
M
T
A
V
H
G
R
F
T
R
Frog
Xenopus laevis
NP_001088420
1303
140252
T565
A
K
M
N
T
L
D
T
L
G
Q
T
A
L
H
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
G395
C
R
K
L
L
S
S
G
Q
L
Y
S
I
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
R502
G
D
L
D
T
V
R
R
I
V
L
N
N
P
I
Honey Bee
Apis mellifera
XP_396483
1166
127309
E490
P
S
G
T
D
D
A
E
A
Q
L
L
E
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
L481
S
E
N
I
Q
K
I
L
Q
A
E
D
Q
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
98.9
N.A.
96.5
72.2
N.A.
86.8
23.2
87.1
21.8
N.A.
59.4
62.7
N.A.
63.6
Protein Similarity:
100
99.6
99.7
99.1
N.A.
97
80.3
N.A.
89.1
37.4
90.9
37.3
N.A.
71.7
72.8
N.A.
74.6
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
0
93.3
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
13.3
93.3
20
N.A.
26.6
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
47
0
8
8
8
16
0
0
54
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
8
54
0
0
0
8
8
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
8
8
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
8
0
0
8
0
8
0
54
8
0
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
54
% H
% Ile:
0
0
0
8
0
0
8
0
8
0
0
0
8
0
8
% I
% Lys:
8
54
8
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
16
16
54
0
8
54
8
16
8
0
62
16
% L
% Met:
0
0
54
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
54
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
16
8
54
0
16
0
0
% Q
% Arg:
0
8
0
0
0
0
8
8
0
0
0
16
0
8
8
% R
% Ser:
8
16
0
8
0
8
8
16
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
8
16
0
8
47
0
0
0
54
0
8
0
% T
% Val:
0
0
8
0
0
8
0
0
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _